Isotonix白藜蘆醇配方粉末 | ShopGlobal.com

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Scientific Studies Which Support Isotonix® Resveratrol:

· Aggarwal B et al. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Research. 24(5A):2783-840, 2004.

· Bauer, J. H., et al. An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster. Proc Natl Acad Sci U S A. 101:12980-12985, 2004.

· Baur J et al. Resveratrol improves health and survival of mice on a high-calorie diet.
Nature. 444(7117):337-42, 2006.

· Belguendouz, L., et al. Resveratrol inhibits metal ion-dependent and independent peroxidation of porcine low-density lipoproteins. Biochemical Pharmacology. 53(9):1347-1355, 1997.

· Bhat K et al. Biological effects of resveratrol. Antioxidants and Redox Signaling. 3(6):1041-64, 2001. Review.

· Borra M et al. Mechanism of human SIRT1 activation by resveratrol. Journal of Biological Chemistry. 280(17):17187-95, 2005.

· Chen Y. Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice. Surgery.136(1):57-66, 2004.

· Dario et al. Resveratrol prolongs life span and retards the onset of age-related markers in a short-lived vertebrae. Current Biology, 2006.

· Ding, X. Z., et al. Resveratrol inhibits proliferation and induces apoptosis in human pancreatic cancer cells. Pancreas. 25(4):71-76, 2002.

· Dong Z. Molecular mechanism of the chemopreventive effect of resveratrol. Mutation Research. 523-524:145-150, 2003.

· Donnelly L et al. Anti-inflammatory Effects of Resveratrol in Lung Epithelial Cells: Molecular Mechanisms. Am J Physiol Lung Cell Mol Physiol, 2004 .

· Faria A et al. Antioxidant properties of prepared blueberry (Vaccinium myrtillus) extracts. Journal of Agricultural and Food Chemistry. 53(17):6896-902, 2005.

· Frémont L. Biological effects of resveratrol. Life Sciences 66:663-673, 2000.

· Fremont, L., et al. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sciences. 64(26):2511-2521, 1999.

· Garvin S et al. Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo. Cancer Letters. 231(1):113-22, 2006.

· Goh S et al. The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms. Antioxidant Redox Signal. 9(1):101-13, 2007.

· Hao H et al. Mechanisms of cardiovascular protection by resveratrol. Journal of Medicinal Food. 7(3):290-298, 2004.

· Heynekamp J et al. Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB. Journal of Medicinal Chemistry. 49(24):7182-9, 2006.

· Holmes-McNary M and Baldwin A Jr. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase. Cancer Research. 60:3477-3483, 2000.

· Hou D et al. Molecular Mechanisms Behind the Chemopreventive Effects of Anthocyanidins. Journal of Biomedicine and Biotechnology. 2004: (5):321-325, 2004.

· Hou D. Potential mechanisms of cancer chemoprevention by anthocyanins. Current Molecular Medicine. 3(2):149-159, 2003.

· Howitz, K. T., et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 425(6954):191-6, 2003.

· Hung L et al. Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes. Cardiovascular Research. 47:549-555, 2000.

· Hung L et al. Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms. Free Radicals in Biology and Medicine. 36(6):774-81, 2004.

· Hwang J et al. Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway. Annals NY Academy of Sciences . 1095:441-8,2007.

· Ignatowicz E and Baer W. Resveratrol, a natural chemopreventive agent against degenerative diseases. Polish Journal of Pharmacology. 53(6):557-69, 2001.

· Jang M et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 275:218-220, 1997.

· Jang M et al. Cancer chemopreventive activity of resveratrol. Drugs in Experimental Clinical Research. 25:65-77, 1999.

· Kaeberlein M et al. Substrate-specific activation of sirtuins by resveratrol. Journal of Biological Chemistry. 280(17):17038-45, 2005.

· Kim, Y. A., et al. Antiproliferative effect of resveratrol in human prostate carcinoma cells. Journal of Medicinal Food. 6(4):273-280, 2003.

· Kopp P. Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the \'French paradox\'? European Journal of Endocrinology. 138(6):619-620, 1998.

· Kundu, J. K., et al. Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. Biofactors. 21(1-4):33-39, 2004.

· Lagouge M et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT-1 and PGC-1alpha. Cell. 127(6):1109-22, 2006.

· Lepoivre M et al. Resveratrol, a remarkable inhibitor of ribonucleotide reductase. FEBS Letters. 421:277-279, 1998.

· Lin J et al. Chemoprevention of cancer and cardiovascular disease by resveratrol.
Proceedings of the National Science Council Republic of China . 23(3):99-106, 1999. Review.

· Manna S et al. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappaB, activator protein-1 and apoptosis: potential role of oxygen intermediates and lipid peroxidation. Journal of Immunology. 164(12):6509-6516, 2000.

· Manna S et al. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappaB, activator protein-1 and apoptosis: potential role of oxygen intermediates and lipid peroxidation. Journal of Immunology. 164(12):6509-6516, 2000.

· Martín A et al. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Biochemical Pharmacology. 67(7):1399-410, 2004.

· Martín A et al. The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model. British Journal of Pharmacology. 147(8):873-85, 2006.

· Martinez J and Moreno J. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production. Biochemical Pharmacology. 59:865-870, 2000.

· Mgbonyebi O. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells. International Journal of Oncology. 12(4):865-869, 1998.

· Nielsen M et al. Resveratrol reverses tumor-promoter-induced inhibition of gap-junctional intercellular communication. Biochemical and Biophysical Research Communications. 275:804-809, 2000.

· Olas B and Wachowicz B. Resveratrol and vitamin C as antioxidants in blood platelets. Thrombosis Research. 106(2):143-8, 2002.

· Olas B and Wachowicz B. Resveratrol reduces oxidative stress induced by platinum compounds in blood platelets. General Physiology and Biophysics. 23(3):315-26, 2004.

· Olas B et al. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thrombosis Research. 107(3-4):141-5, 2002.

· Olas B et al. Resveratrol protects against peroxynitrite-induced thiol oxidation in blood platelets. Cellular and Molecular Biology Letters. 9(4A):577-87, 2004.

· Pace-Asciak C et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta. 235:207-219, 1995.

· Pace-Asciak C et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta. 235:207-219, 1995.

· Picard F et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature. 429(6993):771-776, 2004.

· Porcu M et al. The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. Trends in Pharmacological Sciences 26, 2005.

· Pozo-Guisado, E., et al. Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB. International Journal of Cancer 115(1):74-84, 2005.

· Provinciali M et al. Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. International Journal of Cancer. 115(1):36-45, 2005.

· Sato M et al. Journal of Cardiovascular Pharmacology. 35(2):263-268, 2000.

· Schneider Y et al. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. Cancer Letters. 158(1):85-91, 2000.

· Sinclair D et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 2006.

· Sovak M. Grape extract, resveratrol, and its analogs: a review. Journal of Medicinal Food. 4(2):93-105, 2001.

· Subbaramaiah K et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. Journal of Biological Chemistry. 273:21875-21882, 1998.

· Subbaramaiah K et al. Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Annal NY Academy Sciences. 889:214-223, 2000.

· Szende B et al. Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures. Experimental and Molecular Medicine. 32(2):88-92, 2000.

· Tsai S et al. Suppression of nitric oxide synthase and the down-regulation of the activation of NF-kappaB in macrophages by resveratrol. British Journal of Pharmacology 126:673-680, 1999.

· Wang Z et al. Effects of red wine and wine polyphenol resveratrol on platelet aggregation in vivo and in vitro. International Journal of Molecular Medicine. 9(1):77-9, 2002.

· Yi W et al. Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis. Journal of Agricultural and Food Chemistry 53(18):7320-9, 2005.

· Zou J et al. Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits. Int J Mol Med. 11(3):317-20, 2003.

· Zou J et al. Suppression of mitogenesis and regulation of cell cycle traverse by resveratrol in cultured smooth muscle cells. International Journal of Oncology. 15:647-651, 1999.